Latin Name: Helicia nilagirica Bedd
CAS No.: 80154-34-3
Molecular Formula: C13H16O7
Active ingredients: Helicid/Helicidum
Specification:Helicid 97% 98%
Use Part :Fruit
Appearance: white needle crystal powder
Mesh size:80 Mesh
Test Method: HPLC
- Product Description
Helicia Nilagirica Extract Powder – Premium Natural Sleep Support Ingredient
Botanical extracts are the basis of modern health formulations, especially in the area of sleep problems and regulation of the nervous system. Helicia Nilagirica Extract Powder is a concentrated botanical extract from the fruit of Helicia nilagirica standardised to contain consistent levels of Helicid, a naturally occurring glycoside chemical that has been shown to have sedative-hypjnotic effects. This extract provides manufacturers with a solid plant-based alternative for the development of sleep-aid supplements, anti-anxiety formulations and nerve-calming goods. Its molecular stability and excellent bioavailability make it appropriate for various uses in the pharmaceutical, nutraceutical and cosmetic sectors
Technical Specifications
|
Parameter |
Specification |
||
|
Product Name |
Helicia Nilagirica Extract Powder (Helicid) |
||
|
CAS Number |
80154-34-3 |
||
|
Active Ingredient |
Helicid |
||
|
Molecular Formula |
C13H16O7 |
||
|
Molecular Weight |
284.26 g/mol |
||
|
Purity Grade |
97% / 98% / 99.5% (HPLC) |
||
|
Source Material |
Helicia nilagirica fruit |
||
|
Appearance |
White needle crystal powder |
||
|
Mesh Size |
80 Mesh |
||
|
Solubility |
Soluble in hot water, ethanol; slightly soluble in cold water |
||
|
Test Method |
High-Performance Liquid Chromatography (HPLC) |
||
|
Shelf Life |
24 months (sealed, cool, dry, light-protected storage) |
||
|
Certifications |
ISO9001, HALAL, KOSHER, cGMP, HACCP, Non-GMO, Vegan |
||
| Test Item | Standard Requirement | Test Result | Judgment |
|---|---|---|---|
| Appearance | white needle crystal powder | white needle crystal powder | Complies |
| Identification | HPLC retention time matches 5-HTP reference standard | Positive identification | Complies |
| 5-HTP Content (HPLC) | 98.0% ~ 101.0% | 99.38% | Complies |
| Loss on Drying | ≤5.0% | 2.67% | Complies |
| Total Ash | ≤7.0% | 3.94% | Complies |
| Acid Insoluble Ash | ≤1.5% | 0.66% | Complies |
| pH (1% aqueous solution) | 4.0~6.0 | 4.9 | Complies |
| Single Unknown Impurity | ≤0.10% | 0.04% | Complies |
| Total Related Impurities | ≤0.40% | 0.16% | Complies |
| Particle Size | 100 mesh pass rate ≥98% | 99.6% | Complies |
| Solubility | Soluble in water and aqueous ethanol; slightly soluble in pure ethanol | Conforms | Complies |
| Lead (Pb) | ≤2.0 ppm | 0.37 ppm | Complies |
| Arsenic (As) | ≤2.0 ppm | 0.22 ppm | Complies |
| Cadmium (Cd) | ≤0.3 ppm | Not Detected | Complies |
| Mercury (Hg) | ≤0.1 ppm | Not Detected | Complies |
| Pesticide Residues | Compliant with international herbal residue limits | Complies | Complies |
| Total Aerobic Microbial Count | ≤1000 CFU/g | 48 CFU/g | Complies |
| Yeast & Mold Count | ≤100 CFU/g | Not Detected | Complies |
| Escherichia coli | Negative per gram | Negative | Complies |
| Salmonella spp. | Negative per 25g | Negative | Complies |
| Staphylococcus aureus | Negative per gram | Negative | Complies |
Why Choose Us?
Shaanxi Rebecca Biotechnology Co., Ltd. is an integrated producer that specialises in the research, production, and global distribution of plant extracts. We use state-of-the-art drying at elevated temperatures, micronization technologies to protect bioactive components and provide uniform particle size distribution.
What We Do Best:
· Quality Assurance: Every batch undergoes third-party testing for heavy metals, pesticide residues, and microbial limits, complying with EU EC396 and EU 2023/915 standards
· Customization Capability: OEM/ODM services available with flexible dosage forms including powders, tablets, hard capsules, and soft capsules
· Global Supply Chain: Efficient logistics network ensuring rapid, secure delivery worldwide with proper temperature-controlled storage
· Raw Material Traceability: Sourcing from certified planting bases in Yunnan, India, and Southeast Asia with pre-inspection protocols eliminating contaminated materials
· Technical Support: Professional formulation guidance to help you develop market-competitive products
Our commitment extends beyond manufacturing—we partner with clients to deliver natural, safe, and effective product solutions that meet international quality benchmarks.

Production Process
High-purity Helicid is produced by a strict multi-stage procedure to retain the maximum amount of the active component and remove impurities:
Step 1: Material Preparation – The suitable fruits of Helicia nilagirica are sorted and cleaned well to remove defected specimens and they are coarse crushed under controlled conditions.
Step 2: Extraction – Closed low-temperature water-ethanol countercurrent extraction completely dissolved the helicid glycoside components without thermal degradation.
Step 3 Filtration – Fruit fibres, suspended particles and macromolecular contamination are removed by plate-and-frame and membrane precision filtration systems.
Step 4: Purification – Ethanol precipitation separates inactive polysaccharides and tannins, while activated carbon decolorization eliminates plant pigments and trace pesticide residues.
Step 5: Concentration – The ethanol solvents are recovered by low temperature vacuum concentration without damaging the integrity of the active monomers.
Step 6: Crystallisation – Crystallisation by gradient cooling recrystallisation to isolate trace homologous impurities, to obtain high-purity Helicid crystals.
Step 7: Drying & Blending – Vacuum drying at low temperature minimises oxidative discolouration. Precision sieving and three dimensional bulk blending ensures purity, colour and solubility batch-to-batch uniformity.
Step 8: Packing – The best protection for international shipping is double layers of light-proof vacuum nitrogen-filled aluminium foil bags and outer fibre drums.
Step 9: Quality Control – Comprehensive physical, chemical, and microbial compliance testing with full traceability documentation.
This systematic approach provides the pharmaceutical grade Helicia Nilagirica Extract Powder with medicinal efficacy during its shelf life.

Product Benefits & Applications
Core Functional Advantages:
· Supports natural sleep onset and maintains sleep quality through GABAergic neurotransmission modulation
· Exhibits natural sedative effects beneficial for anxiety relief formulations
· Features advanced sustained-release properties for optimized blood concentration stability
· Demonstrates high stability under standard storage conditions
· Contains no artificial additives, GMOs, or synthetic compounds
Industry Applications:
Your formulation possibilities include sleep improvement capsules, neurasthenia relief tablets, migraine management supplements, anti-stress calming beverages, soothing skincare serums, and sensitive skin repair lotions. The powder form can be easily incorporated into a variety of dosage forms for optimum formulation flexibility.

Packaging & Delivery
We know that the success of your business depends on the integrity of your products in transit. In our packaging we have a multi-layer protection system:
Primary Packaging: Double-layer pharmaceutical grade aluminium foil bags with vacuum nitrogen-flushing to prevent moisture absorption and oxidation. Photosensitive chemicals are protected from UV degradation by light-proof polymers.
Secondary Packaging : High strength fibre drums (25kg net weight typical) protect the product mechanically against impact during handling and transportation.
Labelling: For smooth customs clearance, each container’s batch number, manufacturing date, expiration date, storage directions, and compliance certifications.
Logistics Options: We work with world famous carriers to provide air freight (3-7 days), express shipping (5-10 days) and sea freight (25-35 days) according to your urgency and budget needs. Temperature regulated containers are ideal for shipping across large distances.
Documentation: For seamless customs processing, export documentation must be complete, including: Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), phytosanitary certifications and certificates of origin.
Minimum Order Quantity: Flexible MOQ from 1kg for trial order, discounted price structures for bulk purchase above 100kg.

FAQ
Q: Do you differentiate oral pharmaceutical/food grade and cosmetic topical grade with independent microbiological standards?
A: Yes, we provide distinct grades with customised microbial control indexes. Batch-specific microbiological test reports are available upon request.
Q: How do you maintain batch consistency for annual bulk orders?
A: Deviation is reduced by large-batch three-dimensional blending combined with fixed standardised extraction settings. For long-term clients, priority production scheduling and quarterly fixed-price agreements are available.
Q: What are the storage conditions and shelf life?
A: Shelf life up to 24 months sealed cold dry and protected from light. Do not store in direct sunshine or extreme heat for a long time in logistics and warehousing.
Contact Us
Whether you're developing a new sleep supplement line or enhancing existing products, our Helicia Nilagirica Extract Powder provides the botanical efficacy your customers seek.
Email: information@sxrebecca.com.
_1730691017423.webp)













