Beta Nicotinamide Mononucleotide Powder

Shaanxi Rebecca Biotechnology Co., Ltd is a professional provider of pharmaceutical grade nutraceutical components with strict quality methods. We use advanced enzymatic synthesis technology and have strict quality control methods in our manufacturing facility.

Our Core Strengths:

· Full Enzymatic Production Route: We utilize bio-catalytic synthesis that produces pure β-configuration NMN without toxic intermediates or ineffective α-isomers

· Multiple Purity Grades: Offering 99.0% food grade, 99.5% premium grade, and 99.9% pharmaceutical grade to match your formulation requirements

· Advanced Testing Capabilities: Every batch undergoes HPLC purity analysis, ICP-MS heavy metal screening, ICH Q3C solvent residue testing, and microbial examination

· Stability Enhancement Options: Cyclodextrin inclusion modification available for aqueous formulations requiring extended stability

· Flexible Customization: OEM/ODM services supporting various dosage forms including powders, tablets, hard capsules, soft capsules, and functional beverages

· Robust Supply Chain: Global logistics network with vacuum nitrogen-filled light-proof packaging ensuring product integrity during international shipping

· Comprehensive Documentation: Complete COA, stability data, and independent third-party test reports provided for regulatory compliance

The better the quality of your ingredients the better the chances of your formula succeeding. We deliver consistency, purity, and technical assistance throughout your product development.

Our enzymatic bio-catalytic way is the cleanest manufacturing way for the high purity Beta Nicotinamide Mononucleotide Powder:

Step 1 - Substrate Preparation: Food-grade ribose-5-phosphate and pharmaceutical-grade nicotinamide are dissolved in purified water and sterile-filtered to provide contamination-free starting materials.

Step 2 - Enzymatic Synthesis: The NAMPT enzyme complex catalyses the reaction in aqueous phase at controlled room temperature creating NMN in β-configuration only without chemical side reactions or isomer formation.

Step 3 - Impurity Removal: Ultrafiltration removes leftover enzyme proteins and nanofiltration concentrates the target molecule to significantly reduce impurity levels.

Step 4 - Deep Purification: Ion exchange resins remove inorganic salts, pigments and trace byproducts assuring outstanding whiteness and few impurities.

Step 5 - Concentration: Vacuum concentration below 40 degrees Celsius without light prevents thermal deterioration and maintains molecular conformity.

Step 6 - Recrystallisation: The gradient temperature controlled crystallisation enables to separate the residual substrates and degradation products. The specified purity levels are met by multiple cycles of recrystallisation.

Step 7 - Drying: Fine crystalline powder can be obtained via Low temperature vacuum drying without heat induced degradation.

Step 8 - Optional Modification: Cyclodextrin inclusion complexation can improve aqueous stability in liquid formulations.

Step 9 - Packaging: Particle size and three dimensional batch homogenisation assure consistent results. Double layer aluminium foil bags with nitrogen flushing to protect from light, oxygen and moisture.

Step 10 - Quality Release: Extensive analytical testing results in the generation of a batch-specific COA with full traceability documentation.

This systematic strategy avoids the use of hazardous reagents and improves the yield and purity as compared to chemical synthetic approaches.

We understand the product is photosensitive and hygroscopic, and that is why we have special packaging protocols:

Primary Packaging: Double layer pharmaceutical aluminium foil bags, light blocking, vacuum sealed and nitrogen flushed to reduce oxygen exposure.

Secondary Packaging: Moisture resistant fibre barrels with internal polyethylene liners properly marked with batch numbers, manufacturing dates and storage instructions.

Choose Quantity:

· Sample sizes: 10g-100g for formulation trials

· Standard commercial: 1kg, 5kg, 10kg

· Bulk industrial: 25kg fiber drums (customizable)

Shipping Methods:

· Express courier (FedEx, DHL, UPS): 3-7 days for samples and small orders

· Air freight: 7-10 days for medium volumes with temperature-controlled handling

· Sea freight: 25-35 days for bulk shipments with refrigerated container options

Transit Protection: All shipments are packed with temperature indicators and desiccant packs We offer accelerated stability test data showing product integrity at the high temperature and humidity conditions seen during international travel.

Documents: Certificate of Analysis, Material Safety Data Sheet and Phytosanitary Certificate if needed and independent third party test reports for each cargo for customs clearance.

During delivery, our logistics coordination team is available to give you with real-time tracking of your shipment.

Q: How is the enzymatic production process different from chemical synthesis?

A: Our enzymatic pathway uses bio-catalysis in pure aqueous solution at room temperature to produce solely the $\beta$-active configuration, without the hazardous intermediates, solvent residues, or ineffective $\alpha$-isomers that are present in chemical synthesis.

Q: Do you have any stability statistics for long-distance shipping?

A: Yes, we have conducted accelerated degradation testing under ICH circumstances which demonstrate our vacuum, nitrogen-filled, light-proof packaging retains purity at >98% following a simulated 30-day high temperature/high humidity shipment.

Q: Is there a modified NMN for liquid formulations?

A: Sure. Our cyclodextrin encapsulated grade greatly enhances the stability in aqueous solutions, reducing yellowing and deterioration in oral liquids and beauty serums.

Q: What testing is done to ensure it meets EU import regulations?

A: All batches are subjected to ICH Q3C residual solvent analysis, heavy metals screening by ICP-MS according to EU requirements, and full microbial testing. Customs requirements are reported in separate independent reports.

contact us today for samples, technical specifications, or custom formulation support for Beta Nicotinamide Mononucleotide Powder:

Email: information@sxrebecca.com