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St.John’s Wort Extract
Botanical Source:Hypericum perforatum L.
Other Name：Hypericin, Hypericum perforatum extract.
Active ingredients：Hypericins
Specification：0.3%；0.5%
Appearance: Dark brown to black Powder
Test Method: UV/HPLC
Solubility: Slightly Soluble in water，Soluble in ethanol, dimethyl sulfoxide, methanol, acetone, ethylmethylketone, pyridine and sodium hydroxide.
Molecular Formula:C30H16O8
Molecular Weight: 504.44
CAS No.: 548-04-9
MOQ: 1kg
Sample: 20g
Delivery: FedEx, DHL, Ship by air, Ship by sea.
Certifications: ISO, HACCP, KOSHER, HALAL
- Product Description
Introduction
Hypericin is an extract from St.John’s Wort Extract of Hypericum perforatum L（leaf of Hypericum perforatum L. Hypericum perforatum, known as perforate St John’s- wort, common Saint John’s wort , is a flowering plant in the family Hypericaceae.）. It was first isolated from the plant Hypericum perforatum L. of the Hypericaceae family by humans in 1957. It belongs to the Bisanthrone compounds and is the most biologically active substance in Hypericum perforatum L. It appears as a dark brown to black powder, has a slightly bitter taste, is slightly soluble in water, and can emit a special fragrance. It has the effects of inhibiting the central nervous system and sedation. When added to health supplements, it can enhance immunity and is also used as an antidepressant in Europe, especially in Germany.
why choose us?
- Top Quality: We use high-quality materials and maintain a strict quality control system. From raw material sourcing to product assembly, every production step is carefully managed by dedicated personnel.
- Professional R&D Center: Our R&D team boasts 15 years of experience in the plant extract industry.
- Fast Shipping: Most products are in stock.
- Price Competitiveness: Low minimum order quantity and highly competitive pricing.
Certificate of Analysis
Application
Pharmaceutical manufacturing: St.John’s Wort Extract is mainly used in pharmaceutical production, especially in the development of antidepressant drugs. It is widely used to treat mild to moderate depression, and compared to traditional antidepressants, it has fewer side effects.
Food additives: St.John’s Wort Extract can also be used as a food additive to enhance the color, flavor and nutritional value of food.
Cosmetics: In the cosmetics field, the extract of St.John’s Wort can be used as a skin conditioner, moisturizer, skin protectant, antioxidant, hair conditioner and antibacterial agent. Its anti-inflammatory, antioxidant and moisturizing skin care effects are suitable for people of all skin types and age groups.
1. Agriculture: The active ingredient of the St.John’s Wort Extract, Hypericins, has a remarkable antiviral effect and can be used in the fields of virus suppression for avian influenza, foot-and-mouth disease, and swine fever.
In conclusion, the extract of St.John’s Wort Extract（Hypericum perforatum extract） has extensive applications in various fields such as pharmaceuticals, health supplements, cosmetics, food additives, and agriculture.
Physical and chemical properties
Stability
Hypericin is highly sensitive to light, which is the most significant factor in its degradation, but it is relatively stable in the dark at low temperatures (e.g., -20 °C). Higher temperatures and the presence of certain substances, like pyridine, also accelerate its breakdown. Proper storage involves protection from light and cool temperatures, and formulating it in specific vehicles like PEG 400 or encapsulated in nanoparticles can significantly improve its long-term stability.
I. Key Factors Affecting Hypericin Stability:
1.Light: Light is the most aggressive factor, causing degradation in both extract and standard solutions.
2.Temperature: Higher temperatures lead to more rapid degradation, while cool storage (e.g., -20°C) preserves it.
3.Solution Medium: Hypericin in extract solutions shows better stability compared to standard solutions under various conditions.
4.Chemical Environment: The presence of substances like pyridine significantly accelerates its breakdown.
II.How to Maintain Hypericin Stability:
1.Store in the Dark: Protect samples from light during storage.
2.Use Cold Temperatures: Store solid hypericin and its solutions at low temperatures (e.g., -20°C).
3.Formulation:
3.1 PEG 400: This vehicle effectively maintains hypericin stability at both 4°C and 37°C for extended periods.
3.2 Nanoparticles: Encapsulation in biodegradable nanocarriers can preserve hypericin and its antibacterial photoactivity.
3.3 Protein Binding: Binding to plasma proteins like albumin or lipoproteins can enhance its water solubility and potentially its stability for transport.
In summary: While hypericin is known for its instability, careful control of light exposure and temperature, along with appropriate formulation, can effectively preserve its integrity.
Solubility
Hypericin is insoluble in water and most nonpolar solvents but soluble in polar organic solvents like ethanol, methanol, DMSO, and acetone, as well as in alkaline aqueous solutions and with agents like polyvinylpyrrolidone (PVP) or beta-cyclodextrins to enhance water solubility. Its low solubility in biological media limits its medical applications, prompting research into methods like creating complexes or using drug delivery systems to improve it.
Packing
For powder products, we usually send the products together with cartons or fiber drums.For liquid products, we usually send the product together with a plastic.
Our packaging methods are 1 kg/aluminum bag, 25 kg/box, and 25 kg/barrel. For some products that require special packaging during transportation, we will carry out more detailed packaging.
Transportation
We support shipping by air, sea, FedEx, DHL, TNT, EMS, UPS, SF, and other carrier.
Our laboratory and Factory
As a professional plant extract supplier, our quality inspection department is equipped with the most advanced testing and identification instruments, such as UPLC, HPLC, UV and TT (active ingredients) GC and GC-MS (solvent residue), ICP-MS ( Heavy metals), GC/LC-MS-MS (pesticide residues), HPTLC and IR (identification), ELIASA (ORAC value), PPSL (irradiation residues), microbial detection, etc.
As professional manufacturers and suppliers, we offer Korean Ginseng Extract with confidence in its quality and effectiveness. We provide free samples and MSDS (Material Safety Data Sheets) to ensure our customers are fully informed and satisfied with their purchase. Our high-quality technical R&D team, experienced personnel, and excellent marketing team are dedicated to serving customers globally, with a strong focus on product market development and after-sales service.
FAQ
Q: How is your St.John’s Wort Extract different from others in the market?
A: Our St.John’s Wort Extract is sourced for its superior purity and is third-party tested for quality assurance.
Q: Can you provide samples?
A: Yes, we offer free samples for quality evaluation before bulk purchase.
Q: What are your payment terms?
A: We accept T/T, L/C, and other major payment methods, with flexible terms based on order size.
Q: How do you handle international shipping?
A: We have established logistics partners for efficient and cost-effective global shipping.
Contact us
To view our brochure or discuss a bulk order, contact us at information@sxrebecca.com.
