【Another name】: Scutellaria Baicalensis Extract
【Latin name】:Scutellaria baicalensis Georgi
【CAS No.】: 491-67-8
【Active ingredients】: Baicalein
【Molecular Formula】: C15H10O5
【Molecular Weight】: 270.24
【Specification】: Baicalein Min 98%, HPLC
【Appearance】: Yellow crystalline powder
【Test Method】: HPLC
【Solubility】: Soluble in DMSO (slightly) and methanol (slightly).
- Product Description
Baical Skullcap Root Extract: Premium Botanical Ingredient for Advanced Formulations
The global botanical extract market still needs scientifically validated and naturally efficacious ingredients. Baical Skullcap Root Extract (Scutellaria baicalensis Georgi) is a complex phytochemical extract standardised for high-purity baicalein concentration. This flavonoids-rich extract is a solution to formulation difficulties of nutraceuticals, cosmetics and pharmaceuticals. It offers reliable anti-inflammatory and antioxidant benefits by optimising bioavailability and stability under a wide range of processing conditions. Our extract is molecularly intact and extracted under regulated processes so you can be certain you are getting a dependable active component that fulfils strict international quality norms.
Baical Skullcap Root Extract Specifications
|
Parameter |
Value |
|
|
CAS Number |
491-67-8 |
|
|
Molecular Formula |
C15H10O5 |
|
|
Molecular Weight |
270.24 g/mol |
|
|
Active Constituent |
Baicalein ≥98.0% (HPLC) |
|
|
Appearance |
Fine yellow crystalline powder |
|
|
Particle Size |
80–200 mesh (customizable) |
|
|
Loss on Drying |
≤2.0% |
|
|
Solubility |
Soluble in DMSO, methanol, ethanol |
|
|
Melting Point |
Approximately 264°C |
|
|
Shelf Life |
24 months (sealed, cool, dark storage) |
|
| Test Item | Specification | Test Result |
|---|---|---|
| Appearance | Yellow‑brown fine powder | Yellow‑brown fine powder |
| Assay (Baicalin) | ≥85.0% (HPLC) | 85.42% |
| Loss on Drying | ≤5.0% | 2.86% |
| Total Ash | ≤7.0% | 3.71% |
| Particle Size | 100% pass 80 mesh | Complies |
| Lead (Pb) | ≤10 ppm | 1.05 ppm |
| Arsenic (As) | ≤2 ppm | 0.32 ppm |
| Cadmium (Cd) | ≤1 ppm | 0.14 ppm |
| Mercury (Hg) | ≤0.1 ppm | <0.05 ppm |
| Total Plate Count | ≤10 000 cfu/g | 720 cfu/g |
| Yeast & Mold | ≤1 000 cfu/g | 36 cfu/g |
| E. coli | Negative / 10g | Negative |
| Salmonella | Negative /10g | Negative |
Why Choose Us
Shaanxi Rebecca Biotechnology Co., Ltd. is a combination of vertical integration and precision production.
Our company's R&D team adopts modern high temperature drying and ultra-fine grinding technology to keep the biological activity in the process.
3D blending techniques enable the capacity to be scaled to accommodate large requests while retaining batch uniformity.
All our facilities are equipped with HPLC, UV-Vis spectrophotometry and microbiological testing technologies that verify every batch complies with international standards.
We have ISO9001, HALAL, KOSHER, HACCP and FSSC22000 certificates to prove our dedication to quality management.
Customisation services range from specification changes to dosage form creation to address your particular formulation needs.

Source & Traceability
We work with GAP approved planting bases in northern China that are suitable for Scutellaria baicalensis with loam soils of pH 6.0-7.5.
The roots are purchased as raw material and are thoroughly inspected to remove any contaminated or substandard roots.
Each batch contains purchase documents and cultivation data, providing the entire chain of custody from the field to the final extract.
Our supply chain management emphasises organic agricultural techniques to meet the EU EC396 limits for pesticide residues and the EU 2023/915 requirements for contaminants.
Grade designations vary from 10:1 extracts for common use to 98% baicalein pharmaceutical grade for the most severe regulatory conditions.

Solubility & Stability Characteristics
Baical Skullcap Root Extract is well soluble in polar organic solvents such as ethanol, propylene glycol and glycerin and somewhat soluble in cold aqueous solutions.
Liquid formulations are much improved in hot water dissolving, although clarity is improved in weak alkaline circumstances.
Do not let it come into contact with strongly acid media (pH <4.0) in which it will precipitate.
Thermal stability is maintained below 70 °C during short-term processing, but prolonged exposure above 85 °C leads to degradation of glycosidic bonds.
The extract is somewhat light-sensitive and is packed in light-proof containers to avoid oxidative discolouration.
Good pH stability: 4.2-7.8 best.
Compatible with most personal care and nutritional supplement matrices.
Hygroscopic properties necessitate vacuum sealed inner packaging for shipments over humid climates.

Manufacturing Process
The manufacturing cycle starts with selecting and cleaning of approved roots and coarse crushing to increase the surface area.
Closed-loop low-temperature ethanol-water extraction with dual-solvent countercurrent flow is used to maximise flavonoid production and minimise thermal degradation.
Target chemicals are concentrated and pigments are removed by macroporous resin adsorption, while fibrous wastes are removed by multi-stage filtering and centrifugation.
Gradient elution showed high selectivity for the separation of baicalein from coextracted flavonoids.
Vacuum concentration using light shielding recovers solvents at lower pressure, maintaining thermolabile components.
Aseptic spray drying of concentrated extracts yields fine powders with good flowability.
Precision sieving guarantees particle consistency, while three-dimensional mixing homogenises batches to remove purity and colour differences.
The aluminium foil double-layer bags are put into food-grade fibre drums for warehousing and transit to avoid moisture and light.

Applications & Benefits
Dietary Supplements: Develop anti-inflammatory capsules and immune-support powders using baicalein’s ability to regulate cytokine release and pathways of oxidative stress. For Liver Protection and Respiratory Health Products.
Cosmetic Formulations: Use in anti-redness serums and sensitive skin lotions at levels of 0.5%–2.0%. The extract suppresses inflammatory mediators caused by environmental stresses, surpassing synthetic alternatives in barrier repair formulations.
Pharmaceutical Applications 1. Reference standard of research-grade or traditional medicine patents in the field of flavonoids. High purity is required by pharmaceutical synthesis.

Quality Assurance
Each production batch is subject to thorough testing: Baicalein concentration was confirmed by HPLC, heavy metals (Pb, As, Cd, Hg) were screened by ICP-MS, and microbiological tests were used to ensure compliance with edible and cosmetic-grade limitations. We occasionally have third-party labs confirm our own findings, thereby strengthening data integrity. Traceability from raw material origin to final packaging and batch records are maintained for regulatory audits. ISO22000 and cGMP compliance ensures that the production environment meets food safety and pharmaceutical requirements correspondingly.

Packaging & Delivery
Standard packaging consists of double-layer vacuum-sealed aluminum foil bags containing 1 kg or 5 kg increments, nested within 25 kg food-grade fiber drums.
Custom packaging options include smaller retail units (100 g, 500 g) or bulk intermediate bulk containers (IBCs) for large-scale manufacturers.
Labeling adheres to customer branding guidelines with multilingual regulatory information.
Shipping methods span air freight for urgent orders, sea freight for cost-effective bulk transport, and express courier services for sample requests.
Temperature-controlled logistics options preserve extract stability during transit across varied climates. Lead times range from 7 to 15 business days post-payment confirmation, with expedited handling available for established partners.

FAQ
Q: Can you provide microbial reports for each batch?
A: Yes, we supply independent microbial limit test reports distinguishing oral and topical grades per batch upon request.
Q: How do you ensure color consistency across shipments?
A: Large-batch three-dimensional blending combined with standardized extraction parameters minimizes purity and color deviation. Long-term contracts include quarterly fixed-price agreements.
Q: What documentation supports regulatory filings?
A: We provide CoA, MSDS, allergen declarations, and non-GMO affidavits. Heavy metal and pesticide residue reports align with EU and USDA organic standards.
Q: Is the extract suitable for vegan formulations?
A: Absolutely. Our extraction process uses plant-derived solvents and avoids animal-origin processing aids.
Q: How should I store the product after opening?
A: Reseal containers immediately in cool, dry, dark conditions. Use within six months of opening to maintain potency.
Contact us
For technical inquiries or sample requests, contact our Baical Skullcap Root Extract’s team at information@sxrebecca.com. We're ready to support your formulation goals with reliable botanical solutions.
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